Medical Xpress'Hole in Heart' Defect May Raise Stroke RiskWebMD6 in the Journal of the American Medical Association. "We were surprised about the high magnitude of the risk of stroke in patients with PFO after surgery," Eikermann said. "The patients we studied did not have any sign or symptom of stroke prior to ...A hole in the heart increases post-surgical risk of strokeMedical XpressElevated Perioperative Stroke Risk with PFOMedPage Todayall 3 news articles »