New possible target for rapid antidepressants found - Chemical & Engineering News

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New possible target for rapid antidepressants foundChemical & Engineering NewsRonald S. Duman, of Yale University, led the effort to test the new compound as an antidepressant. In rats with depressionlike symptoms, an oral dose of NV-5138 rapidly penetrated the brain and, within one hour, activated mTORC1 in the prefrontal ...