MedShadow (blog)Quick Hits: Troubled Birth Control Device, Antidepressants and Blood Clots & MoreMedShadow (blog)Posted July 20, 2018. Via FDA. Taking antidepressants along with having depression itself may be associated with a higher risk of potentially life threatening blood clots. Venous thromboembolism is a blood clot that develops in the leg, groin, arm, or ...